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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTPRA All Species: 17.27
Human Site: S176 Identified Species: 38
UniProt: P18433 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18433 NP_002827.1 802 90600 S176 K K Y K Q A G S H S N S K Q A
Chimpanzee Pan troglodytes XP_001158332 793 89670 S176 K K Y K Q A G S H S N S F R L
Rhesus Macaque Macaca mulatta XP_001114682 793 89729 S176 K K Y K Q A G S H S N S F R L
Dog Lupus familis XP_534366 793 89602 S176 K K Y K Q A G S H S N S F R L
Cat Felis silvestris
Mouse Mus musculus P18052 829 93679 S176 K K Y K Q A G S H S N S F R L
Rat Rattus norvegicus Q03348 796 90242 Q176 L R F K K Y K Q A G S H S N S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516836 648 74144 P58 D M E P Q S V P L L A R S P S
Chicken Gallus gallus Q6YI48 1434 161661 S327 E I E Y R M T S G P W S E V H
Frog Xenopus laevis NP_001089394 819 92510 R193 I I V L Y M L R F K K Y K Q A
Zebra Danio Brachydanio rerio A4IFW2 1909 213435 G447 E P N G Q I R G Y R I Y Y T S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P16621 2029 229038 N457 Y K V Y Y T T N S N Q P E A S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 98.2 95 N.A. 91.5 93.3 N.A. 74.4 23.9 80.4 22.5 N.A. 20.3 N.A. N.A. N.A.
Protein Similarity: 100 98.8 98.2 96.6 N.A. 93.3 95.6 N.A. 77.4 36.4 87.1 31.3 N.A. 28.6 N.A. N.A. N.A.
P-Site Identity: 100 80 80 80 N.A. 80 6.6 N.A. 6.6 13.3 20 6.6 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 86.6 86.6 86.6 N.A. 86.6 40 N.A. 20 33.3 20 26.6 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 46 0 0 10 0 10 0 0 10 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 19 0 19 0 0 0 0 0 0 0 0 0 19 0 0 % E
% Phe: 0 0 10 0 0 0 0 0 10 0 0 0 37 0 0 % F
% Gly: 0 0 0 10 0 0 46 10 10 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 46 0 0 10 0 0 10 % H
% Ile: 10 19 0 0 0 10 0 0 0 0 10 0 0 0 0 % I
% Lys: 46 55 0 55 10 0 10 0 0 10 10 0 19 0 0 % K
% Leu: 10 0 0 10 0 0 10 0 10 10 0 0 0 0 37 % L
% Met: 0 10 0 0 0 19 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 10 0 10 46 0 0 10 0 % N
% Pro: 0 10 0 10 0 0 0 10 0 10 0 10 0 10 0 % P
% Gln: 0 0 0 0 64 0 0 10 0 0 10 0 0 19 0 % Q
% Arg: 0 10 0 0 10 0 10 10 0 10 0 10 0 37 0 % R
% Ser: 0 0 0 0 0 10 0 55 10 46 10 55 19 0 37 % S
% Thr: 0 0 0 0 0 10 19 0 0 0 0 0 0 10 0 % T
% Val: 0 0 19 0 0 0 10 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 10 0 46 19 19 10 0 0 10 0 0 19 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _